For research and educational purposes only. Not intended for human consumption.
Melanotan I
Extensively Studied- •FDA-approved SCENESSE® for EPP
- •MC1R selective photoprotection
- •Clinical safety data published
Melanocortin Receptor Agonist | Afamelanotide
Overview
What is Melanotan I?
Melanotan I (afamelanotide) is a synthetic α-MSH analog that selectively targets MC1 receptors to stimulate melanin production. An FDA-approved implant (SCENESSE®) exists for erythropoietic protoporphyria. Research-grade injectable is studied for photoprotective and tanning effects.
Key Benefits
Precise dosing control, visible tanning within 1-2 weeks, more MC1R selective than Melanotan II with fewer side effects.
Mechanism of Action
Subcutaneous injection delivers MT-I with 100% bioavailability. 30-minute half-life requires multiple daily injections for sustained MC1R activation.
Molecular Information
Pharmacokinetics
Research Indications
Enhanced Tanning
Deeper, longer-lasting tan with reduced UV exposure.
Photoprotection
Increased melanin provides natural UV protection.
Research Protocols
Disclaimer: Research-grade MT-I is not FDA-approved for tanning.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Initial Tanning | 0.25mg | 2x daily | Subcutaneous |
| Maintenance | 0.5mg | 1x daily | Subcutaneous |
Timing: Multiple daily injections due to 30-minute half-life. Best with minimal UV 2-3 hours post-injection.
Peptide Interactions
How to Reconstitute
Important: Always use bacteriostatic water (BAC). Sterile technique is essential.
Allow vials to reach room temp
Swab with alcohol
Draw 2ml BAC water
Inject slowly
Swirl gently
Refrigerate 2-8°C
Dosing Calculator
Calculate your injection volume with visual dosing guide
To obtain 250 mcg from this solution:
Draw 0.10 mL=10 units
(1 mL = 100 units on any insulin syringe)
Draw to this mark for 250 mcg
This calculator is for research purposes only. Always verify calculations and consult protocols.
Quality Indicators
Third-party testing
HPLC purity >98%.
Clear reconstitution
Clear and colorless.
Premixed solutions
Peptides degrade rapidly in solution.
What to Expect
- •Days 1-3: Mild nausea, flushing
- •Days 3-7: Initial skin darkening
- •Week 1-2: Noticeable tanning
- •Week 2-4: Peak tanning effects
Side Effects & Safety
Side Effects
- •Research peptide - not approved for tanning
- •Mild nausea and flushing
- •Monitor moles and skin changes
- •Maintain UV protection despite tanning
When to Stop
- •New or changing moles
- •Persistent nausea
- •Unusual skin reactions
References
1 StudiesSafety Profile (2006)
Human | 147 subjects | Minimal adverse events
Excellent tolerability with transient nausea/flushing.
View StudyQuick Start Guide
Research Disclaimer
Melanotan I is sold for laboratory research purposes only and is not intended for human or animal consumption. The information provided on this page is compiled from published research, veterinary studies, and anecdotal reports for educational purposes. This content does not constitute medical advice, diagnosis, or treatment recommendations. Any research involving Melanotan I must comply with all applicable local, state, and federal regulations. BioInfinity Lab makes no claims regarding the safety or efficacy of Melanotan I for any purpose. Consult qualified professionals for any research applications.