All Research Compounds

5-Amino-1MQ is a selective, membrane-permeable small-molecule NNMT inhibitor (EC50 ~2.3 µM in adipocytes) that blocks nicotinamide methylation to 1-MNA, preserving nicotinamide for NAD+ salvage, elevating NAD+ 1.2-1.6 fold, and activating Sirt1 for metabolic benefits including ~35% adipose reduction without appetite effects.

AOD-9604 is a 16-amino-acid C-terminal fragment (aa 177-191 + N-terminal Tyr) of human GH that retains lipolytic activity via β3-adrenergic receptor upregulation without growth-promoting, diabetogenic, or IGF-1-stimulating effects. Phase 2b obesity trials failed, but cartilage regeneration research continues.

BPC-157 is a synthetic 15-amino-acid peptide originally derived from a larger gastric protective protein fraction identified in stomach mucosa. It has attracted sustained scientific interest because it appears to interact with multiple biological pathways involved in tissue integrity, vascular signaling, and stress responses in preclinical research models.

Cagrilintide is a novel long-acting lipidated amylin analog targeting dual amylin and calcitonin receptors. Phase 3 trials show 22.7% weight loss when combined with glp1-s (CagriSema).

CJC-1295 with DAC is a synthetic 30-amino acid GHRH analog with a Drug Affinity Complex that enables covalent albumin binding, extending half-life from ~7 minutes (native GHRH) to 5.8-8.1 days. Phase 1/2 trials demonstrated GH increases of 2-10 fold for 6+ days and IGF-1 rises of 1.5-3 fold lasting 9-11 days per dose.

Mod GRF 1-29 is a tetrasubstituted GHRH analog (Ala2, Gln8, Ala15, Leu27) with ~30-minute half-life (vs ~7 min native GHRH) due to DPP-IV resistance. Lacking DAC's albumin binding, it produces acute pulsatile GH release mimicking physiology, synergizing with GHRPs via complementary cAMP/Ca2+ pathways.

Epithalon is a synthetic tetrapeptide that activates telomerase primarily by upregulating hTERT gene expression, extending telomeres by approximately 33.3% in human somatic cells and increasing proliferative potential beyond the Hayflick limit (from 34 to 44+ passages in fetal fibroblasts). Developed by Vladimir Khavinson from pineal gland extract research.

FOXO4-DRI is a D-retro-inverso peptide that selectively induces apoptosis in senescent cells by disrupting FOXO4-p53 nuclear complexes, causing p53 nuclear exclusion, mitochondrial translocation, BAX activation, cytochrome C release, and caspase-3/7-mediated intrinsic apoptosis while sparing healthy cells.

GHK-Cu is a naturally occurring copper-binding tripeptide that promotes wound healing through keratinocyte migration, increased VEGF/bFGF expression, decorin and collagen production, elastin and glycosaminoglycan synthesis, while remodeling tissue via MMP-2/MMP-9 activation and TIMP-1/TIMP-2 modulation to organize collagen and elastin fibers.

GLP1-S is a GLP-1 receptor agonist peptide analog with 94% homology to human GLP-1. It is FDA-approved for type 2 diabetes and chronic weight management under various brand names. Research-grade glp1-s is studied separately from approved pharmaceutical products.

GLP2-T is an FDA-approved dual GIP/GLP-1 receptor agonist with imbalanced potency favoring GIPR (equal to native GIP) over GLP-1R (~5-fold weaker than native GLP-1). SURPASS trials showed HbA1c reductions of 1.8-2.4% and weight loss of 7-12 kg; SURMOUNT trials achieved 15-22.5% body weight reduction over 72 weeks.

GLP3-R is a first-in-class triple agonist peptide targeting GIP, GLP-1, and glucagon receptors simultaneously. Currently in multiple Phase 3 clinical trials (2024-2025) by Eli Lilly for obesity, type 2 diabetes, and related conditions, with Phase 2 data showing unprecedented 24.2% mean weight loss at 48 weeks.

Humanin is a 24-amino acid mitochondrial-derived peptide originally discovered in surviving neurons of Alzheimer's disease patients. It exerts neuroprotective effects primarily by inhibiting apoptosis via BAX binding, mitigating oxidative stress, preserving mitochondrial function, and counteracting neurotoxic insults like amyloid-beta in multiple disease models.

Ipamorelin is the first GHRP with GHRH-like selectivity, binding GHSR-1a (ghrelin receptor) to stimulate pulsatile GH release with EC50 = 1.3 nmol/L and Emax = 85% comparable to GHRP-6, but without ACTH/cortisol elevation even at >200-fold above GH ED50. Lower plasma clearance (5-fold slower than GHRP-6) with ~50% nasal bioavailability.

MOTS-c is a 16-amino-acid mitochondrial-derived peptide (MDP) encoded within the 12S rRNA gene of mitochondrial DNA. Discovered in 2015, it functions as an 'exercise mimetic' through AMPK activation, NAD+ elevation, and sirtuin activation, with levels declining approximately 21% in elderly populations and higher levels observed in centenarians.

Oxytocin is a nine-amino-acid peptide hormone produced in the hypothalamus. FDA-approved for labor induction and postpartum hemorrhage. Intranasal forms researched for autism and social disorders.

Sermorelin is the 29-aa minimal bioactive GHRH fragment with full receptor equivalence to 44-aa native GHRH. Previously FDA-approved (Geref, 1990s) for pediatric GH deficiency, it preserves pulsatile GH secretion and hypothalamic feedback. Available via compounding; ~10-20 min half-life requires bedtime dosing.

TB-500 is a synthetic 7-amino-acid fragment (Ac-LKKTETQ) from thymosin beta-4's actin-binding site that promotes tissue repair through G-actin sequestration, ROCK1 downregulation, cell migration, progenitor cell mobilization, angiogenesis, and anti-inflammatory effects. Phase 2 human trials show 61% improvement in wound reepithelialization by day 7.

Tesamorelin is the only FDA-approved GHRH analog (2010), indicated for HIV-associated lipodystrophy. The 44-aa sequence with N-terminal trans-3-hexenoic acid modification stimulates endogenous pituitary GH, reducing visceral adipose tissue 10-18% vs placebo while preserving feedback regulation.

AHK-Cu is a synthetic copper-binding tripeptide that demonstrates targeted activity on dermal papilla cells and hair follicles, stimulating hair growth and skin regeneration.

Ara 290 is an erythropoietin-derived peptide that activates tissue-protective pathways without stimulating red blood cells. FDA Orphan Drug status with Phase 2 trial success.

Bioglutide is a first-in-class oral quadruple receptor agonist targeting IGF-1, GLP-1, GIP, and glucagon. Phase 2 showed 13.8% weight loss with muscle preservation.

Cerebrolysin is a standardized neuropeptide preparation derived from purified porcine brain proteins, containing bioactive peptides that exhibit neurotrophic properties for stroke recovery and cognitive enhancement.

Dihexa is a synthetic oligopeptide derived from angiotensin IV that acts as an HGF mimetic, binding hepatocyte growth factor with high affinity and enhancing c-Met receptor signaling to promote synaptogenesis 7-fold greater than BDNF, neurogenesis, and memory restoration in preclinical Alzheimer's models.

Follistatin-344 is a glycoprotein that competitively blocks myostatin's ActRIIB binding, interrupting SMAD2/3 signaling to enable muscle growth. AAV1-FS-344 gene therapy in mdx mice produced 15-fold serum follistatin increase, significant muscle mass/strength gains sustained 560+ days without cardiac or reproductive adverse effects.

Glutathione is a tripeptide called the body's 'master antioxidant,' playing critical roles in neutralizing free radicals, detoxification, and immune support.

HCG is a glycoprotein hormone that activates LH receptors, FDA-approved for hypogonadism, infertility, and cryptorchidism. Commonly used with TRT to maintain testicular function.

Hexarelin is a synthetic hexapeptide growth hormone releasing peptide (GHRP) and one of the most potent GH secretagogues studied. It uniquely binds to cardiac CD36 receptors providing GH-independent cardioprotection.

Human Growth Hormone is a 191 amino acid polypeptide FDA-approved for growth hormone deficiency, regulating growth, metabolism, and body composition.

IGF-1 LR3 is a synthetic 83-amino-acid IGF-1 analog with an Arg3 substitution and 13-aa N-terminal extension that reduces IGFBP binding, extending half-life from ~15 min to 20-30 hours. Activates PI3K/Akt/mTOR pathway for protein synthesis while suppressing FoxO-mediated ubiquitin-proteasome degradation via GSK3β inhibition.

Kisspeptin is a family of neuropeptides that acts as a master regulator of the reproductive system, potently stimulating GnRH secretion. Used in fertility research and as a diagnostic tool for reproductive disorders.

L-Carnitine is an FDA-approved amino acid derivative essential for fatty acid transport into mitochondria, with injectable form providing 100% bioavailability.

Mazdutide is a dual GLP-1 and glucagon receptor agonist in Phase 3 trials showing up to 14% weight loss and significant liver fat reduction in MASH studies.

Melanotan I is a synthetic α-MSH analog that selectively targets MC1 receptors to stimulate melanin production. FDA-approved implant (SCENESSE®) exists for erythropoietic protoporphyria.

Melanotan II is a synthetic cyclic α-MSH analog with non-selective melanocortin receptor activity: MC1R (melanogenesis via cAMP/MITF/tyrosinase), MC4R (CNS sexual/appetite effects), MC3R (energy homeostasis). NOT approved for human use; regulatory agencies have issued warnings due to safety concerns.

MK-677 is a selective ghrelin receptor agonist that stimulates growth hormone release without suppressing natural production. This orally active compound increases IGF-1 levels, improves sleep quality, and supports body composition changes.

NA Semax Amidate is an enhanced, stabilized version of Semax with superior bioavailability and extended half-life for advanced cognitive enhancement and neuroprotection.

NAD+ is a vital coenzyme found in every cell that plays crucial roles in energy production, DNA repair, and cellular metabolism. Levels naturally decline with age, and supplementation supports cellular health and longevity.

Omberacetam is a synthetic nootropic dipeptide 1000x more potent than piracetam, enhancing memory, learning, and neuroprotection through BDNF/NGF upregulation.

Orforglipron is a novel oral non-peptide GLP-1 receptor agonist showing up to 14.7% weight loss, offering injectable-comparable efficacy without injections.

PT-141 (bremelanotide/Vyleesi) is the first FDA-approved treatment targeting neurological sexual desire via MC4R agonism in hypothalamic/limbic regions. Approved 2019 for premenopausal HSDD at 1.75 mg SC, RECONNECT trials showed ~1 additional satisfying sexual event per 2 months vs placebo.

Selank is a synthetic heptapeptide analog of tuftsin with additional glyproline residues, developed in Russia and investigated for anxiolytic, nootropic, neuroprotective, and immunomodulatory effects through GABAergic and neurotransmitter system modulation.

Semax is a synthetic heptapeptide analog of ACTH(4-10) that enhances BDNF and NGF expression, modulates dopaminergic, serotonergic, and cholinergic systems, and demonstrates neuroprotective effects through inhibition of nitric oxide synthesis, improved cerebral blood flow, and anti-inflammatory gene modulation in stroke research.

SNAP-8 is a synthetic octapeptide that inhibits SNARE complex formation to reduce muscle contractions and expression lines, achieving up to 63% wrinkle depth reduction.

Survodutide is a dual glucagon and GLP-1 receptor agonist in Phase 3 trials for obesity and MASH/NASH, showing up to 19% weight loss and significant liver fat reduction.

Thymosin alpha-1 is a 28-amino-acid thymic peptide that modulates immunity primarily through TLR-2 and TLR-9 agonism, promoting T-cell maturation, reversing T-cell exhaustion, activating NK cells, and balancing pro/anti-inflammatory responses. Approved in 35+ countries for viral hepatitis and cancer immunotherapy adjunct.

Thymosin Beta-4 is a naturally occurring 43-amino acid peptide that plays crucial roles in tissue repair, wound healing, and cellular regeneration. It promotes angiogenesis and reduces inflammation.

VIP is a 28-amino acid neuropeptide with potent vasodilatory, immunomodulatory, and neuroprotective properties. FDA breakthrough therapy designation for ARDS/COVID-19 respiratory failure.

The Wolverine Stack combines BPC-157 and TB-500 for synergistic tissue repair. A 2021 clinical study showed 87.5% of patients experienced knee pain relief with this combination.

Adalank is an enhanced Selank derivative with acetylation and amidation for superior stability, researched for anxiety reduction, cognitive enhancement, and stress resilience without dependency.

Adamax is an enhanced Semax derivative with adamantane modification for superior BBB penetration, researched for cognitive enhancement, neuroprotection, and neuroplasticity.

Adipotide is a chimeric peptide that targets and destroys blood vessels feeding white adipose tissue, causing rapid fat loss through apoptosis of fat cells. Highly experimental with significant side effects.

Cartalax is a synthetic tripeptide bioregulator that supports cartilage, connective tissue, and cellular regeneration through modulation of proliferation markers and apoptosis pathways.

Cyclic glycine-proline is an endogenous cyclic dipeptide that regulates IGF-1 bioavailability and shows neuroprotective and cognitive benefits in research.

DSIP is a naturally occurring nonapeptide discovered in 1974 that promotes delta wave sleep, reduces stress, and modulates multiple neurotransmitter systems including GABA and endogenous opioids.

KPV is the C-terminal tripeptide (Lys-Pro-Val) of α-MSH that exerts anti-inflammatory effects primarily through intracellular mechanisms independent of melanocortin receptors. It is transported into cells via PepT1, where it inhibits NF-κB signaling, reducing pro-inflammatory cytokines (IL-6, IL-12) while not affecting anti-inflammatory IL-10.

Lipo-C is a lipotropic injection containing Methionine, Inositol, Choline (MIC), and B vitamins that support liver function and fat metabolism.

LL-37 is the only human cathelicidin-derived antimicrobial peptide, promoting wound healing through anti-biofilm/antibacterial activity, enhanced re-epithelialization via keratinocyte/fibroblast/endothelial cell proliferation, angiogenesis, and MAPK pathway activation (ERK, JNK, p38) for collagen deposition and tissue repair.

P21 is a CNTF-derived tetrapeptide that enhances neurogenesis and cognitive function by activating CNTF receptor pathways without the side effects of full-length CNTF.

PE-22-28 is a synthetic peptide derived from sortilin propeptide that acts as a TREK-1 potassium channel blocker, showing rapid antidepressant effects in preclinical models.

PEG-MGF is a pegylated form of the IGF-1 splice variant MGF that activates muscle satellite cells for repair and regeneration with extended half-life.

Pinealon is a synthetic tripeptide (EDR) derived from pineal gland research that shows neuroprotective effects and may support cognitive function and circadian rhythm regulation.

Prostamax is a synthetic tetrapeptide bioregulator from the Khavinson family that demonstrates prostate-specific tissue effects and epigenetic chromatin regulation properties.

SHLP-2 is a 28-aa mitochondrial-derived peptide (MT-RNR2 encoded) with chaperone-like activity binding CXCR7 (EC50 ~0.97 µM). It restores OXPHOS complexes, reduces ROS, improves insulin sensitivity (50% higher glucose infusion rates), and activates POMC neurons for thermogenesis. A K4R variant provides Parkinson's protection.

SLU-PP-332 is a synthetic 'exercise mimetic' that activates metabolic pathways engaged during physical exercise, showing 12% weight loss and 70% endurance increase in animal studies. NOT FOR HUMAN USE.

SS-31 (elamipretide) is a mitochondria-targeting tetrapeptide that binds to cardiolipin in the inner mitochondrial membrane, stabilizing cristae structure, preventing cardiolipin peroxidation, and improving electron transport chain function. FDA-approved for Barth syndrome (FORZINITY), with ongoing trials for heart failure and mitochondrial diseases.

Tesofensine is a triple monoamine reuptake inhibitor showing up to 12.8% weight loss in trials, one of the most effective oral weight loss agents studied.

Testagen is a synthetic tetrapeptide bioregulator that supports anterior pituitary function, thyroid hormone release, and may indirectly support testosterone through TSH modulation.

Thymulin is a zinc-dependent thymic hormone that promotes T-cell differentiation and has anti-inflammatory properties, declining with age.

Bacteriostatic water is sterile water containing 0.9% benzyl alcohol as a preservative, inhibiting bacterial growth for 28-day multiple-use vial compatibility in laboratory peptide reconstitution applications.

Sterile water for injection is USP-grade purified water sterilized and packaged in single-use vials for laboratory reconstitution of lyophilized compounds requiring preservative-free diluent.

Fat Blaster is a lipotropic injection blend combining L-Carnitine, Methionine-Inositol-Choline (MIC), B vitamins, and NADH for enhanced fat metabolism support.

The Glow Protocol is a multi-peptide skin rejuvenation complex featuring BPC-157, TB-500, and GHK-Cu for comprehensive anti-aging and tissue repair.

KLOW is a four-peptide regenerative blend (GHK-Cu + TB-500 + BPC-157 + KPV) building on the GLOW protocol with enhanced anti-inflammatory effects from KPV.

TRT (Testosterone Replacement Therapy) is FDA-approved for treating male hypogonadism, using testosterone cypionate or enanthate esters for sustained hormone levels.