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For research and educational purposes only. Not intended for human consumption.

KLOW Protocol

Limited Research
Updated Dec 2025

Four-Peptide Regenerative Blend | GHK-Cu + TB-500 + BPC-157 + KPV

Injectable
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2-3.2mg total blend
Once daily
Injectable
Subcutaneous: Rotate between abdomen
4-6 weeks
Typical duration
2-8°C
Refrigerated

Overview

What is KLOW Protocol?

KLOW is a research peptide combination that builds upon the GLOW protocol by adding KPV for enhanced anti-inflammatory effects. This 80mg blend typically contains 50mg GHK-Cu, 10mg TB-500, 10mg BPC-157, and 10mg KPV in a 5:1:1:1 ratio. While individual components have varying levels of research support, no clinical trials have examined this specific four-peptide combination. The protocol remains investigational with theoretical benefits based on complementary mechanisms.

Key Benefits

Theoretical synergistic effects from four peptides - tissue repair, anti-inflammation, cellular regeneration. KPV may reduce injection site reactions compared to GLOW. Single injection versus four separate peptides for convenience.

Mechanism of Action

Each peptide contributes different mechanisms: GHK-Cu modulates genes and stimulates collagen, TB-500 enhances cell migration, BPC-157 upregulates growth factors, KPV inhibits NF-κB for anti-inflammatory effects.

Molecular Information

80mg total blend
Weight
0
amino acids
Four-peptide regenerative blend
Type
Amino Acid Sequence:
N/A - Multi-peptide combination
* GHK-Cu 50mg + TB-500 10mg + BPC-157 10mg + KPV 10mg (5:1:1:1)

Pharmacokinetics

Peak
Variable
Half-life
Component-dependent
Cleared
Variable
100%50%0%0h6h12h18h24h
Peak
Half-life
Cleared
Individual component estimates

Research Indications

Multi-Modal Healing

Addresses tissue repair through multiple complementary pathways.

Enhanced Tolerability

KPV may reduce injection site reactions compared to GLOW protocol.

Convenience Factor

Single injection versus four separate peptides.

Research Protocols

Disclaimer: No clinical trials have examined this specific four-peptide combination. Individual components have varying levels of research support. FDA has not approved any component for therapeutic use.

GoalDoseFrequencyRoute
Common Research Protocol3.2mg total (2mg GHK-Cu, 400mcg each TB500/KPV/BPC-157)Once dailySubcutaneous
Starter/Titration Protocol2mg total (1.25mg GHK-Cu, 250mcg each TB500/KPV/BPC-157)Once dailySubcutaneous
Cycling ProtocolAs above4-6 weeks on, 2-4 weeks offSubcutaneous

Timing: Evening dosing is common practice but not based on research. Some prefer morning administration.

Peptide Interactions

How to Reconstitute

Important: Always use bacteriostatic water (BAC). Sterile technique is essential.

1

Clean vial top with alcohol pad

2

Add 2-5mL bacteriostatic water (4mL creates 20mg/mL)

3

Gently swirl - do not shake

4

Solution should be clear to slightly cloudy

5

Label with date and concentration

6

Store in refrigerator immediately

7

Use within 4-6 weeks

Dosing Calculator

Calculate your injection volume with visual dosing guide

FINAL CONCENTRATION
2.50mg/mL
Each milliliter contains 2.50 mg of peptide
VISUAL REFERENCE (RESEARCH USE ONLY)

To obtain 250 mcg from this solution:

Draw 0.10 mL=10 units

(1 mL = 100 units on any insulin syringe)

0102030405060708090100
00.10.20.30.40.50.60.70.80.91.0
0.10 mL
10 units

Draw to this mark for 250 mcg

This calculator is for research purposes only. Always verify calculations and consult protocols.

Quality Indicators

Third-party testing

Look for Janoshik or similar analytical verification.

Reputable research supplier

Established vendors with quality control processes.

Research-only status

Not approved for human use - research purposes only.

Batch variability

Ratios and purity may vary between batches.

No COA provided

Avoid vendors without certificates of analysis.

What to Expect

  • Individual responses vary widely with no predictable timeline
  • Some users report reduced inflammation within days
  • Wound healing effects may take 2-4 weeks if they occur
  • No clinical data exists to set realistic expectations
  • Community polls: 835 responses, 57% currently using, 44% would definitely recommend

Side Effects & Safety

Side Effects

  • No safety studies on four-peptide combination
  • Individual peptides generally well-tolerated in research
  • Injection site reactions common (36% of users) even with KPV
  • Long-term effects completely unknown
  • Quality and contamination risks in unregulated market

When to Stop

  • Adverse effects
  • Signs of infection
  • Unusual symptoms
  • As directed by provider

References

3 Studies

Individual Component Research - GHK-Cu

Human studies | Various protocols | 40+ years research | Wound healing, anti-aging, gene modulation

GHK-Cu has extensive research showing beneficial effects, but studies used GHK-Cu alone, not in combination.

BPC-157 Limited Human Data (2020)

Human pilot | 12 patients | Interstitial cystitis | 10 of 12 complete resolution

One small pilot study showed 10 of 12 patients achieved complete resolution of symptoms. Most BPC-157 research remains in animal models.

No Published Studies on KLOW Combination

No clinical trials | No safety studies | No peer-reviewed research

Despite vendor claims and user reports, no scientific studies have examined the safety or efficacy of the four-peptide KLOW combination.

Quick Start Guide

Typical Dose
2-3.2mg daily (0.1-0.16mL at 20mg/mL)
How Often
Once daily, typically evening
Where to Inject
Subcutaneous: Rotate between abdomen
Timing
Evening administration common but not studied
Effects Timeline
User reports vary - some claim benefits within days, others weeks
Storage
Must refrigerate after reconstitution
Cycle Length
4-6 weeks typical
Break Between
2-4 weeks reported

Research Disclaimer

KLOW Protocol is sold for laboratory research purposes only and is not intended for human or animal consumption. The information provided on this page is compiled from published research, veterinary studies, and anecdotal reports for educational purposes. This content does not constitute medical advice, diagnosis, or treatment recommendations. Any research involving KLOW Protocol must comply with all applicable local, state, and federal regulations. BioInfinity Lab makes no claims regarding the safety or efficacy of KLOW Protocol for any purpose. Consult qualified professionals for any research applications.