For research and educational purposes only. Not intended for human consumption.
Testagen
Limited Research- •TSH regulation mechanism characterized
- •Thyroid-testosterone axis research
- •Khavinson bioregulator protocol studies
KEDG Tetrapeptide | Anterior Pituitary Bioregulator
Overview
What is Testagen?
Testagen (KEDG, Lys-Glu-Asp-Gly) is a synthetic tetrapeptide bioregulator developed by Professor Vladimir Khavinson. Derived from anterior pituitary gland extracts, Testagen is researched for effects on thyroid-stimulating hormone (TSH) release, thyroid function, and downstream testosterone regulation. It may cross cell and nuclear membranes to directly interact with DNA.
Key Benefits
Direct systemic absorption, precise dosing control, bypasses GI degradation, supports anterior pituitary function, potential thyroid and testosterone optimization through TSH modulation.
Mechanism of Action
Testagen (KEDG) crosses cell and nuclear membranes to interact with DNA in anterior pituitary cells, stimulating TSH release and subsequently influencing T3/T4 thyroid hormone production, which correlates with normalized testosterone levels.
Molecular Information
Pharmacokinetics
Research Indications
Anterior Pituitary Support
May stimulate anterior pituitary function, enhancing TSH release.
Thyroid Function Optimization
Studies indicate Testagen may increase TSH, influencing T3/T4 production.
Testosterone Support (Indirect)
By optimizing thyroid function, may indirectly support testosterone levels.
Research Protocols
Disclaimer: No human clinical trials exist. Guidance from preclinical research. Contraindicated in thyroid cancer or hyperthyroidism.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Starting/Titration (Weeks 1-2) | 100mcg | Once daily | SubQ |
| Building (Weeks 3-4) | 150mcg | Once daily | SubQ |
| Standard (Weeks 5-8) | 200mcg | Once daily | SubQ |
| Maximum (Weeks 9-12) | 250-300mcg | Once daily | SubQ |
Timing: Morning administration preferred to align with natural circadian hormone rhythms.
Peptide Interactions
How to Reconstitute
Important: Always use bacteriostatic water (BAC). Sterile technique is essential.
Add 3.0mL BAC water to 20mg vial = 6.67mg/mL
Inject slowly down vial wall
Gently swirl - do NOT shake
Allow to sit if cloudiness, swirl until clear
Store reconstituted at 2-8°C
Dosing Calculator
Calculate your injection volume with visual dosing guide
To obtain 250 mcg from this solution:
Draw 0.10 mL=10 units
(1 mL = 100 units on any insulin syringe)
Draw to this mark for 250 mcg
This calculator is for research purposes only. Always verify calculations and consult protocols.
Quality Indicators
White lyophilized powder
White, fluffy powder cake without clumping.
Clear reconstituted solution
Crystal clear and colorless.
Limited research base
Most research from Russian bioregulator programs.
Discoloration
Yellow/brown indicates degradation.
What to Expect
- •Weeks 1-2: Establishing baseline, minimal effects
- •Weeks 3-4: Subtle improvements in energy and mood
- •Weeks 5-8: Thyroid function optimization, improved metabolic rate
- •Weeks 8-12: Full effects on thyroid-testosterone axis
Side Effects & Safety
Side Effects
- •No human clinical trials - preclinical guidance only
- •Contraindicated in thyroid cancer or hyperthyroidism
- •Monitor thyroid function if on thyroid medications
- •Start with lower dose to assess response
- •Not recommended during pregnancy
When to Stop
- •Thyroid abnormalities
- •Adverse effects
- •As directed by provider
References
2 StudiesHypophysectomized Avian Model Study
Avian | Pituitary-removed birds | Thyroid assessment | Thyroid morphology changes
KEDG peptide associated with changes in thyroid gland morphology and follicle structure even without hypophyseal support.
Thyroid Function Without Hypophyseal Support
Preclinical | TSH modulation | Gene expression analysis
Testagen stimulates TSH release and T3/T4 production even without hypophyseal support.
Quick Start Guide
Research Disclaimer
Testagen is sold for laboratory research purposes only and is not intended for human or animal consumption. The information provided on this page is compiled from published research, veterinary studies, and anecdotal reports for educational purposes. This content does not constitute medical advice, diagnosis, or treatment recommendations. Any research involving Testagen must comply with all applicable local, state, and federal regulations. BioInfinity Lab makes no claims regarding the safety or efficacy of Testagen for any purpose. Consult qualified professionals for any research applications.