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For research and educational purposes only. Not intended for human consumption.

SNAP-8

Well Researched
Updated Dec 2025

Acetyl Octapeptide-3 | Anti-Wrinkle & Expression Line Peptide

TopicalInjectable
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3-10% concentration
2x daily
Topical
Topical: Forehead
Continuous use
Typical duration
4-25°C
Storage

Overview

What is SNAP-8?

SNAP-8 (Acetyl Octapeptide-3) is a synthetic octapeptide developed as a topical alternative to botulinum toxin. It inhibits SNARE complex formation, reducing acetylcholine release and muscle contractions. Clinical studies demonstrate up to 63% wrinkle depth reduction.

Key Benefits

Non-invasive Botox alternative, reduces expression lines by up to 63%, safe for sensitive skin and eye area, no recovery time.

Mechanism of Action

SNAP-8 mimics SNAP-25 protein N-terminal, competing for SNARE complex binding sites, reducing neurotransmitter release and muscle contractions.

Molecular Information

1,075.16 Da
Weight
8
amino acids
Acetylated octapeptide with C-terminal amidation
Type
Amino Acid Sequence:
Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2
* N-terminal acetylation and C-terminal amidation for stability.

Pharmacokinetics

Peak
Variable (topical)
Half-life
N/A
Cleared
N/A
100%50%0%0h6h12h18h24h
Peak
Half-life
Cleared
Topical application

Research Indications

Expression Line Reduction

Up to 63% reduction in wrinkle depth over 28 days.

Forehead Wrinkles

Targets horizontal forehead lines.

Crow's Feet

Reduces periorbital wrinkles.

Research Protocols

Disclaimer: SNAP-8 is a cosmetic ingredient. Results require consistent application.

GoalDoseFrequencyRoute
General Anti-Aging3-5%2x dailyTopical serum
Intensive Treatment5-10%2x dailyTargeted application

Timing: Apply to clean, dry skin before heavier products. Follow with sunscreen in morning.

Peptide Interactions

How to Reconstitute

Important: Always use bacteriostatic water (BAC). Sterile technique is essential.

1

Cleanse face thoroughly

2

Pat dry

3

Apply pea-sized amount to target areas

4

Pat gently - don't rub

5

Allow 2-3 min absorption

6

Follow with moisturizer

Dosing Calculator

Calculate your injection volume with visual dosing guide

FINAL CONCENTRATION
2.50mg/mL
Each milliliter contains 2.50 mg of peptide
VISUAL REFERENCE (RESEARCH USE ONLY)

To obtain 250 mcg from this solution:

Draw 0.10 mL=10 units

(1 mL = 100 units on any insulin syringe)

0102030405060708090100
00.10.20.30.40.50.60.70.80.91.0
0.10 mL
10 units

Draw to this mark for 250 mcg

This calculator is for research purposes only. Always verify calculations and consult protocols.

Quality Indicators

Clear, colorless solution

Clear to slightly yellowish.

pH 3.0-5.0

Optimal for stability.

Cloudy or discolored

Indicates degradation.

What to Expect

  • Day 1-7: Slight smoothing
  • Week 2-3: Initial fine line reduction
  • Week 4: 35% wrinkle reduction
  • Week 6-8: Up to 63% reduction

Side Effects & Safety

Side Effects

  • Generally well-tolerated
  • Perform patch test first
  • Avoid combining with strong acids
  • Not for use during pregnancy

When to Stop

  • Persistent irritation
  • Allergic reaction
  • No improvement after 8 weeks

References

1 Studies

Argireline Anti-Wrinkle RCT

Human | 10% | 4 weeks | 60 subjects | 48.9% anti-wrinkle efficiency

First multicenter RCT showing significant wrinkle reduction.

View Study

Quick Start Guide

Typical Dose
3-10% concentration
How Often
Twice daily
Where to Apply
Topical: forehead
Timing
After cleansing, before moisturizer
Effects Timeline
7 days: smoothing; 28 days: significant reduction; 8+ weeks: maximum
Storage
Solution 4°C; powder room temp
Cycle Length
Continuous use
Break Between
No cycling required

Research Disclaimer

SNAP-8 is sold for laboratory research purposes only and is not intended for human or animal consumption. The information provided on this page is compiled from published research, veterinary studies, and anecdotal reports for educational purposes. This content does not constitute medical advice, diagnosis, or treatment recommendations. Any research involving SNAP-8 must comply with all applicable local, state, and federal regulations. BioInfinity Lab makes no claims regarding the safety or efficacy of SNAP-8 for any purpose. Consult qualified professionals for any research applications.