For research and educational purposes only. Not intended for human consumption.
SLU-PP-332
Limited Research- •Exercise mimetic - no physical activity needed
- •12% weight loss in 28 days (animal)
- •70% endurance increase (preclinical)
Synthetic Pan-ERR Agonist | Exercise Mimetic & Metabolic Modulator
Overview
What is SLU-PP-332?
SLU-PP-332 is a synthetic small-molecule pan-estrogen-related receptor (ERR) agonist developed at Saint Louis University. Often called an 'exercise mimetic,' it activates metabolic pathways typically engaged during physical exercise. Studies show 12% weight loss in 28 days, 70% increased endurance, and enhanced insulin sensitivity. NOT FDA-APPROVED - FOR RESEARCH ONLY. Banned by WADA
Key Benefits
Exercise mimetic without physical activity, 12% weight loss (28 days animal studies), 70% increased endurance, 25% enhanced fatty acid oxidation, improved insulin sensitivity, cardiac protection.
Mechanism of Action
Binds to and activates ERRα/β/γ receptors, upregulates PGC-1α (mitochondrial biogenesis master regulator), activates AMPK pathway, increases mitochondrial density up to 1.8-fold.
Molecular Information
Pharmacokinetics
Research Indications
Weight Loss
12% body weight reduction in 28 days in animal studies.
Insulin Sensitivity
Significantly improved glucose tolerance in obese mice.
Liver Health
Reduced hepatic steatosis and triglycerides.
Research Protocols
Disclaimer: NOT FDA APPROVED. NO HUMAN CLINICAL TRIALS. FOR RESEARCH USE ONLY. Human dosing does not exist.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| RESEARCH ONLY | 50 mg/kg (animal) | Twice daily | IP injection (animals) |
| NO HUMAN DOSE | NOT ESTABLISHED | Awaiting clinical trials | Oral formulation in development |
Timing: Animal studies used IP injection twice daily. Human protocols DO NOT EXIST.
Peptide Interactions
How to Reconstitute
Important: Always use bacteriostatic water (BAC). Sterile technique is essential.
Insoluble in water - use DMSO
Dissolve in pure DMSO first (50-125 mg/mL)
Dilute: 10% DMSO + 10% Tween 80 + 80% PBS
Store DMSO stocks at -80°C
Final DMSO <10% for in vivo use
Dosing Calculator
Calculate your injection volume with visual dosing guide
To obtain 250 mcg from this solution:
Draw 0.10 mL=10 units
(1 mL = 100 units on any insulin syringe)
Draw to this mark for 250 mcg
This calculator is for research purposes only. Always verify calculations and consult protocols.
Quality Indicators
Insoluble in water
Must use DMSO as solvent, not BAC water.
Research chemical only
NOT FOR HUMAN USE - no human safety data.
Products for human consumption
Any product marketed for humans is illegal.
What to Expect
- •Hours 1-6: Metabolic shift toward fat oxidation
- •Week 1: Increased resting energy expenditure
- •Week 2-4: Weight loss, improved glucose tolerance
- •Week 6-8: Cardiac improvements, sustained metabolic benefits
Side Effects & Safety
Side Effects
- •NOT FDA APPROVED - RESEARCH ONLY
- •Human safety profile COMPLETELY UNKNOWN
- •Animal studies show favorable safety at therapeutic doses
- •No liver, kidney, or cardiac toxicity in animals
- •Legal status varies by jurisdiction
When to Stop
- •DO NOT USE - research chemical only
- •Await human clinical trials
- •Any adverse effects
References
2 StudiesERR Agonist Alleviates Metabolic Syndrome (2024)
Mouse | 50 mg/kg | 28 days | 12% weight loss, improved glucose
Landmark study showing weight loss and metabolic improvements.
Exercise Mimetic Response (2023)
Mouse | Running performance | 70% endurance increase
First demonstration that ERR activation replicates exercise effects.
Quick Start Guide
Research Disclaimer
SLU-PP-332 is sold for laboratory research purposes only and is not intended for human or animal consumption. The information provided on this page is compiled from published research, veterinary studies, and anecdotal reports for educational purposes. This content does not constitute medical advice, diagnosis, or treatment recommendations. Any research involving SLU-PP-332 must comply with all applicable local, state, and federal regulations. BioInfinity Lab makes no claims regarding the safety or efficacy of SLU-PP-332 for any purpose. Consult qualified professionals for any research applications.