For research and educational purposes only. Not intended for human consumption.
Selank
Well Researched- •62-patient GAD trial - benzodiazepine equivalent
- •CD4+/CD8+ immune normalization data
- •Bcl6 gene expression research
Synthetic Tuftsin Analog | Anxiolytic & Nootropic Peptide
Overview
What is Selank?
Selank is a synthetic heptapeptide analog of the naturally occurring immune peptide tuftsin, developed by the Russian Academy of Sciences. This anxiolytic and nootropic peptide has been extensively studied for its ability to reduce anxiety, enhance cognitive function, and modulate immune responses without the side effects associated with traditional benzodiazepines. Clinical trials with 62+ patients demonstrate anxiolytic effects equivalent to medazepam without sedation, with additional immunomodulatory benefits including CD4+/CD8+ T cell ratio normalization.
Key Benefits
Benzodiazepine-equivalent anxiolytic effects without sedation or dependency (proven in 62-patient trials), enhanced BDNF expression, improved stress resilience, cognitive enhancement, immune modulation with CD4+/CD8+ normalization, enhanced NK cell activity, no tolerance or withdrawal, and neuroprotective effects.
Mechanism of Action
Positive allosteric modulation of GABA-A receptors (blocking benzodiazepine modulatory activity non-cumulatively), serotonin and dopamine system optimization, enkephalin degradation inhibition, IL-6 and cytokine balance regulation, BDNF upregulation in hippocampus, and Bcl6 gene expression for immune development.
Molecular Information
Pharmacokinetics
Research Indications
Generalized Anxiety Disorder
Clinical trials demonstrate significant reduction in anxiety symptoms comparable to benzodiazepines but without sedation, amnesia, or dependence.
Post-Traumatic Stress Disorder
Emerging research shows effectiveness in PTSD treatment, helping stabilize stress responses and emotional regulation.
Social Anxiety and Performance Stress
Reduces anticipatory anxiety and social stress while maintaining cognitive clarity.
Research Protocols
Disclaimer: Selank is approved in Russia for various conditions. These protocols are for research purposes. Consult a healthcare provider before use.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Mild anxiety relief | 250mcg daily | Once daily | SubQ injection |
| Moderate anxiety/cognitive enhancement | 250mcg twice daily | Morning and evening | SubQ injection |
| Intensive anxiety/stress management | 500mcg daily | Divided doses | SubQ injection |
| Cognitive enhancement/nootropic use | 250-350mcg daily | Morning only | SubQ injection |
| PTSD/trauma support | 250mcg twice daily | Consistent timing | SubQ injection |
Timing: Selank can be injected any time of day. Morning injection may provide better cognitive benefits, while evening injection may enhance relaxation and sleep quality.
Peptide Interactions
How to Reconstitute
Important: Always use bacteriostatic water (BAC). Sterile technique is essential.
Remove Selank vial from refrigeration and allow to reach room temperature for 10-15 minutes
Clean vial tops with alcohol wipes
Calculate appropriate reconstitution volume based on desired concentration
Draw calculated amount of bacteriostatic water into insulin syringe
Insert needle into Selank vial at 45-degree angle against the glass wall
Slowly inject BAC water down the side of the vial to minimize foaming
Gently swirl vial - NEVER shake vigorously
Final solution should be clear and colorless
Label vial with reconstitution date and concentration
Store in refrigerator immediately, use within 30 days
Dosing Calculator
Calculate your injection volume with visual dosing guide
To obtain 250 mcg from this solution:
Draw 0.10 mL=10 units
(1 mL = 100 units on any insulin syringe)
Draw to this mark for 250 mcg
This calculator is for research purposes only. Always verify calculations and consult protocols.
Quality Indicators
White to Off-White Powder
High-quality Selank appears as light, fluffy lyophilized powder without clumping.
Clear Reconstituted Solution
Properly reconstituted Selank should be completely clear and colorless.
Proper Labeling and Batch Information
Legitimate Selank includes clear peptide sequence, purity testing, and batch numbers.
Yellowing, Clumping, or Moisture Exposure
Discolored, clumped, or damp powder indicates degradation.
Persistent Cloudiness After Reconstitution
Cloudiness indicates peptide aggregation or contamination.
Unusual Smell or Burning Sensation
Fresh Selank should be odorless - strong smells may indicate contamination.
What to Expect
- •Mild anxiety reduction within 30-60 minutes of injection
- •Improved mental clarity and focus within 1-3 days
- •Enhanced stress resilience and emotional stability by week 1
- •Better sleep quality and reduced nervous tension
- •Cognitive enhancement effects peak around 1-2 weeks
- •No sedation, drowsiness, or cognitive impairment
- •Sustained benefits may last several days after discontinuation
Side Effects & Safety
Side Effects
- •Start with lowest effective dose (250mcg) to assess individual response
- •Selank has excellent safety profile with minimal reported side effects
- •No known tolerance, dependence, or withdrawal issues reported
- •Can be safely combined with most medications under medical supervision
- •Store properly refrigerated to maintain peptide stability
- •Use sterile injection techniques to prevent infection
When to Stop
- •Allergic reactions
- •Severe mood changes
- •Unusual symptoms
- •If taking multiple psychiatric medications
- •Consult healthcare provider
References
6 StudiesGAD Clinical Trial (62 Patients)
Human | GAD and neurasthenia | Multi-week treatment | Benzodiazepine-equivalent efficacy
Russian clinical trials involving 62 patients with generalized anxiety disorder showed Selank produced anxiolytic effects equivalent to medazepam while avoiding sedation and cognitive impairment.
Expanded GAD Trial (30 Patients)
Human | Multiple psychometric scales | 21 days intranasal | Significant symptom reduction
Demonstrated significant decreases in GAD symptom severity and duration using CGI, Zung, and Hamilton scales, with improved quality of life and no typical benzodiazepine side effects.
Immune Normalization in Anxiety Patients
Human | Anxiety disorder patients | Immune markers | Immunomodulatory effects
Clinical studies documented Selank normalized dysregulated immune parameters, including restoration of CD4+/CD8+ T cell ratios and enhancement of natural killer cell activity.
Quick Start Guide
Research Disclaimer
Selank is sold for laboratory research purposes only and is not intended for human or animal consumption. The information provided on this page is compiled from published research, veterinary studies, and anecdotal reports for educational purposes. This content does not constitute medical advice, diagnosis, or treatment recommendations. Any research involving Selank must comply with all applicable local, state, and federal regulations. BioInfinity Lab makes no claims regarding the safety or efficacy of Selank for any purpose. Consult qualified professionals for any research applications.