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For research and educational purposes only. Not intended for human consumption.

Pinealon

Limited Research
Updated Dec 2025

Tripeptide Bioregulator | Neuroprotection & Circadian Support

OralInjectableNasal
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10-20mg
Once daily
Oral
Oral capsule or sublingual preferred
10-30 days
Typical duration
Room
Storage

Overview

What is Pinealon?

Pinealon (Glu-Asp-Arg/EDR) is a synthetic tripeptide bioregulator developed in Russia that demonstrates unique DNA-interaction capabilities for neuroprotection and circadian rhythm support. It was designed to mimic the regulatory effects of pineal gland-derived peptides on brain function, sleep regulation, and neuroprotective pathways.

Key Benefits

Neuroprotection and cognitive support, circadian rhythm regulation, melatonin pathway support, convenient oral bioavailability, well-tolerated in available studies.

Mechanism of Action

Pinealon binds to specific DNA sequences (GAGG) in promoter regions of genes involved in neuroprotection and melatonin synthesis, upregulating expression of protective factors and supporting pineal function.

Molecular Information

418.4 Da
Weight
3
amino acids
Tripeptide bioregulator
Type
Amino Acid Sequence:
Glu-Asp-Arg (EDR)
* Short peptide designed to cross biological barriers and interact with DNA regulatory sequences

Pharmacokinetics

Peak
1 hr
Half-life
2 hrs
Cleared
~10 hrs
100%50%0%0h6h12h18h24h
Peak
Half-life
Cleared
Limited preclinical data

Research Indications

Cognitive Support

May protect neurons and support cognitive function through gene regulation.

Anti-Aging Brain Effects

Bioregulator approach to supporting brain health during aging.

Research Protocols

Disclaimer: Pinealon is primarily available in Russia/CIS countries. Limited clinical data exists. These protocols are based on available research.

GoalDoseFrequencyRoute
Neuroprotection10-20mgOnce dailyOral (sublingual)
Sleep/Circadian Support10mgOnce daily (evening)Oral (sublingual)
Anti-Aging Protocol10-20mgOnce daily for 10-30 daysOral

Timing: For sleep support, take in the evening. For general neuroprotection, morning dosing is common. Sublingual administration may improve absorption.

Peptide Interactions

How to Reconstitute

Important: Always use bacteriostatic water (BAC). Sterile technique is essential.

1

Pinealon is typically supplied as oral capsules or sublingual tablets

2

For sublingual use, place under tongue and allow to dissolve

3

For capsules, take with water on empty stomach

4

Store at room temperature in original packaging

5

Protect from moisture and direct sunlight

6

Use within expiration date

Dosing Calculator

Calculate your injection volume with visual dosing guide

FINAL CONCENTRATION
2.50mg/mL
Each milliliter contains 2.50 mg of peptide
VISUAL REFERENCE (RESEARCH USE ONLY)

To obtain 250 mcg from this solution:

Draw 0.10 mL=10 units

(1 mL = 100 units on any insulin syringe)

0102030405060708090100
00.10.20.30.40.50.60.70.80.91.0
0.10 mL
10 units

Draw to this mark for 250 mcg

This calculator is for research purposes only. Always verify calculations and consult protocols.

Quality Indicators

Pharmaceutical-grade product

Should come from licensed manufacturer with proper documentation.

Clear labeling

Proper labeling with batch number and expiration.

Limited Western availability

Primarily available in Russia/CIS - verify source quality.

Limited clinical data

Most evidence from Russian literature.

Moisture damage

Tablets should be dry and intact.

What to Expect

  • Week 1: Subtle effects, possible sleep improvement
  • Week 2-3: Potential cognitive and circadian benefits
  • Week 3-4: Full course effects developing
  • Post-cycle: Effects may persist for several weeks
  • Note: Individual responses vary; limited clinical validation

Side Effects & Safety

Side Effects

  • Generally well-tolerated in available studies
  • Limited side effect data due to minimal clinical trials
  • May affect melatonin levels
  • Not recommended during pregnancy or breastfeeding
  • Consult healthcare provider before use

When to Stop

  • Unexpected sleep disturbances
  • Mood changes
  • Allergic reactions
  • As directed by healthcare provider

References

3 Studies

DNA-Binding and Gene Regulation

In vitro | Cell culture | Binds GAGG sequences

Pinealon demonstrated binding to specific DNA sequences in promoter regions, modulating gene expression.

Neuroprotection in Aged Models

Animal study | Various | Cognitive improvements

Studies showed improvements in cognitive parameters in aged animal models.

Pineal Gland Support

Preclinical | Various | Melatonin pathway effects

Evidence of supporting melatonin synthesis and circadian regulation.

Quick Start Guide

Typical Dose
10-20mg
How Often
Once daily
Where to Inject
Oral capsule or sublingual
Timing
Morning for neuroprotection, evening for sleep support
Effects Timeline
Sleep effects: 1-2 weeks; Neuroprotection: 2-4 weeks
Storage
Room temperature, protect from moisture
Cycle Length
10-30 days
Break Between
1-3 months between cycles

Research Disclaimer

Pinealon is sold for laboratory research purposes only and is not intended for human or animal consumption. The information provided on this page is compiled from published research, veterinary studies, and anecdotal reports for educational purposes. This content does not constitute medical advice, diagnosis, or treatment recommendations. Any research involving Pinealon must comply with all applicable local, state, and federal regulations. BioInfinity Lab makes no claims regarding the safety or efficacy of Pinealon for any purpose. Consult qualified professionals for any research applications.