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For research and educational purposes only. Not intended for human consumption.

PEG-MGF

Limited Research
Updated Dec 2025

Pegylated Mechano Growth Factor | IGF-1 Splice Variant

Injectable
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200-400mcg
2-3 times weekly
Injectable
Subcutaneous or intramuscular (bilateral
4-8 weeks
Typical duration
2-8°C
Refrigerated

Overview

What is PEG-MGF?

PEG-MGF (Pegylated Mechano Growth Factor) is a modified IGF-1 splice variant with PEG attached to extend half-life from minutes to hours. MGF activates satellite cells to support muscle repair. A 2011 study showed MGF significantly increased satellite cell proliferation at doses as low as 3ng/ml. Banned by WADA

Key Benefits

Extended half-life through PEGylation, activates satellite cells for muscle repair, may support recovery from mechanical stress or injury.

Mechanism of Action

PEG-MGF activates muscle satellite cells via MAPK/ERK signaling, enhancing protein synthesis and promoting muscle fiber repair.

Molecular Information

~2,888 Da
Weight
24
amino acids
IGF-1Ec splice variant C-terminal peptide
Type
Amino Acid Sequence:
YQPPSTNKNTKSQRRKGSTFEEHK
* PEGylation for extended half-life

Pharmacokinetics

Peak
1-2 hours
Half-life
Several hours
Cleared
~24 hours
100%50%0%0h6h12h18h24h
Peak
Half-life
Cleared
Research data

Research Indications

Satellite Cell Activation

Activates dormant muscle satellite cells for repair.

Enhanced Fusion Potential

Increased fusion potential supporting muscle fiber repair.

Research Protocols

Disclaimer: PEG-MGF is a research chemical with limited human data. Not FDA-approved.

GoalDoseFrequencyRoute
General Recovery200mcg2-3 times weeklySubQ or IM
Targeted Muscle Recovery200-400mcgPost-workout, 2-3x weeklyIM near target

Timing: Post-workout administration aligns with natural MGF upregulation.

Peptide Interactions

How to Reconstitute

Important: Always use bacteriostatic water (BAC). Sterile technique is essential.

1

Allow vial to reach room temp

2

Clean stopper with alcohol

3

Inject BAC water slowly

4

Gently swirl

5

Refrigerate 2-8°C

Dosing Calculator

Calculate your injection volume with visual dosing guide

FINAL CONCENTRATION
2.50mg/mL
Each milliliter contains 2.50 mg of peptide
VISUAL REFERENCE (RESEARCH USE ONLY)

To obtain 250 mcg from this solution:

Draw 0.10 mL=10 units

(1 mL = 100 units on any insulin syringe)

0102030405060708090100
00.10.20.30.40.50.60.70.80.91.0
0.10 mL
10 units

Draw to this mark for 250 mcg

This calculator is for research purposes only. Always verify calculations and consult protocols.

Quality Indicators

White lyophilized powder

White or off-white fluffy cake.

Clear after reconstitution

Crystal clear solution.

Cloudy or particles

Indicates degradation.

What to Expect

  • Week 1-2: Reduced muscle soreness
  • Week 2-4: Enhanced recovery
  • Week 4-8: Optimal muscle repair effects

Side Effects & Safety

Side Effects

  • Not FDA-approved - research chemical
  • Contraindicated with cancer history
  • WADA banned substance
  • Long-term safety unknown

When to Stop

  • Any unusual growths
  • Blood glucose abnormalities
  • As directed by provider

References

1 Studies

MGF Human Muscle Cell Study (2011)

Human satellite cells | In vitro | Significant proliferation at 3ng/ml

Landmark study showing MGF increased satellite cell proliferation.

View Study

Quick Start Guide

Typical Dose
200-400mcg
How Often
2-3 times weekly
Where to Inject
SubQ or IM
Timing
Post-workout
Effects Timeline
Recovery: 2-4 weeks; Optimal: 6-8 weeks
Storage
Refrigerate 2-8°C, use within 3-4 weeks
Cycle Length
4-8 weeks
Break Between
4-8 weeks off between cycles

Research Disclaimer

PEG-MGF is sold for laboratory research purposes only and is not intended for human or animal consumption. The information provided on this page is compiled from published research, veterinary studies, and anecdotal reports for educational purposes. This content does not constitute medical advice, diagnosis, or treatment recommendations. Any research involving PEG-MGF must comply with all applicable local, state, and federal regulations. BioInfinity Lab makes no claims regarding the safety or efficacy of PEG-MGF for any purpose. Consult qualified professionals for any research applications.