For research and educational purposes only. Not intended for human consumption.
Oxytocin
Extensively Studied- •FDA-approved obstetric indications
- •Social cognition research for autism
- •Mental health applications (PTSD, anxiety)
Neurohypophysial Peptide | Social Bonding & Reproductive Hormone
Overview
What is Oxytocin?
Oxytocin is a nine-amino-acid peptide hormone and neuropeptide naturally produced in the hypothalamus. Known as the 'love hormone' or 'bonding hormone,' it plays fundamental roles in social bonding, trust, empathy, sexual reproduction, childbirth, and lactation. FDA-approved for labor induction and postpartum hemorrhage control.
Key Benefits
FDA-approved for labor induction and postpartum hemorrhage control, precise dosing via IV infusion, immediate onset, well-established safety profile.
Mechanism of Action
Binds to oxytocin receptors (OXTR) on uterine smooth muscle cells, triggering calcium influx and myometrial contractions. Also stimulates prostaglandin release.
Molecular Information
Pharmacokinetics
Research Indications
Labor Induction
FDA-approved for initiation or augmentation of uterine contractions when vaginal delivery is indicated.
Postpartum Hemorrhage Prevention
FDA-approved for control of postpartum bleeding through uterine contraction stimulation.
Incomplete Abortion Management
Adjunctive therapy for management of incomplete or inevitable abortion.
Research Protocols
Disclaimer: Injectable oxytocin is used exclusively in clinical settings for labor and delivery. Must be administered only by qualified healthcare professionals. This is not for self-administration.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Labor Induction | 0.5-2 mU/min initial, titrate to 1-2 mU/min every 30-60 min | Continuous IV infusion | Intravenous (diluted) |
| Labor Augmentation | 0.5-1 mU/min initial, increase gradually | Continuous IV infusion | Intravenous (diluted) |
| Postpartum Hemorrhage Prevention | 10 units IM or 10-40 units in IV solution | Single dose after placental delivery | Intramuscular or IV infusion |
| Postpartum Hemorrhage Treatment | 10-40 units in 1L IV fluid | Rate adjusted to control bleeding | Intravenous infusion |
Timing: Onset is immediate (IV) to 3-5 minutes (IM). Effects are short-lived requiring continuous infusion for labor.
Peptide Interactions
How to Reconstitute
Important: Always use bacteriostatic water (BAC). Sterile technique is essential.
This is a hospital/clinical procedure performed by healthcare professionals
Dilute oxytocin in compatible IV solution per facility protocol
Typical dilution: 10 units in 1000mL = 10 mU/mL
Use infusion pump for precise rate control
Monitor uterine contractions and fetal heart rate continuously
Adjust rate based on clinical response and safety parameters
Have emergency medications available (terbutaline for tocolysis)
Dosing Calculator
Calculate your injection volume with visual dosing guide
To obtain 250 mcg from this solution:
Draw 0.10 mL=10 units
(1 mL = 100 units on any insulin syringe)
Draw to this mark for 250 mcg
This calculator is for research purposes only. Always verify calculations and consult protocols.
Quality Indicators
FDA-approved pharmaceutical product
Use only FDA-approved oxytocin injection (Pitocin) from licensed pharmacies.
Clear, colorless solution
Oxytocin injection should be clear without particles or discoloration.
Proper packaging and labeling
Verify lot number, expiration date, and concentration.
Requires clinical setting
Injectable oxytocin should only be administered in clinical settings with proper monitoring.
Cloudy or discolored solution
Do not use if solution appears cloudy or discolored.
What to Expect
- •Used exclusively in clinical/hospital settings
- •Immediate onset of uterine contractions (IV)
- •Requires continuous monitoring of contractions and fetal heart rate
- •Effects diminish rapidly after discontinuation (short half-life ~3-5 min)
- •May cause transient blood pressure changes
- •Common side effects: nausea, vomiting, headache
Side Effects & Safety
Side Effects
- •Must be administered only by qualified healthcare professionals
- •Requires continuous electronic fetal monitoring during labor
- •Uterine hyperstimulation is the primary concern - can cause fetal distress
- •Contraindicated in certain obstetric conditions
- •Water intoxication risk with high doses or prolonged infusion
- •Have tocolytic agents available for uterine hyperstimulation
When to Stop
- •Uterine hyperstimulation
- •Fetal distress
- •Signs of water intoxication
- •Allergic reaction
- •As directed by healthcare provider
References
3 StudiesIntranasal Oxytocin for Obesity (2024)
Human RCT | N=61 | 24 IU four times daily | 8 weeks | No weight loss but improved mental health
Treatment did not result in weight loss but showed significant reduction in caloric intake and improvement in mental health quality of life.
Social Cognition in Schizophrenia (2023)
Human RCT | N=68 | 24 IU twice daily | 12 weeks | Modest social functioning improvement
While no significant advantage on primary outcomes, oxytocin showed modest improvement in social functioning.
Autism Spectrum Disorder Trial (2021)
Human Phase 2 RCT | N=290 | 48 IU daily | 24 weeks | No significant improvement in social functioning
Large RCT found intranasal oxytocin did not significantly improve social functioning in children with ASD.
Quick Start Guide
Research Disclaimer
Oxytocin is sold for laboratory research purposes only and is not intended for human or animal consumption. The information provided on this page is compiled from published research, veterinary studies, and anecdotal reports for educational purposes. This content does not constitute medical advice, diagnosis, or treatment recommendations. Any research involving Oxytocin must comply with all applicable local, state, and federal regulations. BioInfinity Lab makes no claims regarding the safety or efficacy of Oxytocin for any purpose. Consult qualified professionals for any research applications.