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For research and educational purposes only. Not intended for human consumption.

Omberacetam (Noopept)

Well Researched
Updated Dec 2025

Synthetic Dipeptide | Cognitive Enhancement Nootropic

OralNasal
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10-30mg
1-3 times daily
Oral
Oral tablet/capsule or sublingual powder; pair with choline source
4-8 weeks on, 2-4 weeks off
Typical duration
Room
Storage

Overview

What is Omberacetam (Noopept)?

Omberacetam (Noopept/GVS-111) is a synthetic nootropic dipeptide developed in Russia in 1996 for its potent cognitive-enhancing and neuroprotective properties. It functions as a prodrug that converts to cycloprolylglycine (CPG). Research indicates it may enhance memory, learning, and neuroplasticity through BDNF/NGF upregulation at doses 1000x lower than piracetam.

Key Benefits

Rapid oral bioavailability, convenient dosing, memory and learning enhancement, neuroprotection, well-studied in clinical trials.

Mechanism of Action

Rapidly absorbed orally and converted to active metabolite cycloprolylglycine (CPG) which modulates AMPA/NMDA glutamate receptors and enhances cholinergic neurotransmission.

Molecular Information

318.37 Da
Weight
2
amino acids
Synthetic dipeptide nootropic
Type
Amino Acid Sequence:
N-phenylacetyl-L-prolylglycine ethyl ester
* Prodrug converted to cycloprolylglycine (CPG) in vivo

Pharmacokinetics

Peak
20-60 minutes
Half-life
30-60 minutes
Cleared
~3-5 hours
100%50%0%0h6h12h18h24h
Peak
Half-life
Cleared
Clinical data

Research Indications

Memory Enhancement

Improved memory consolidation through enhanced synaptic plasticity and BDNF.

Learning Acceleration

Faster acquisition via AMPA receptor modulation.

Focus and Concentration

Sustained attention through acetylcholine sensitization.

Research Protocols

Disclaimer: Pair with choline source (Alpha-GPC or CDP-Choline) to prevent headaches.

GoalDoseFrequencyRoute
Beginner Cognitive10mg1-2x dailyOral
Standard Cognitive10-20mg2-3x dailyOral
Intensive Enhancement20-30mg2-3x dailyOral (cycled)

Timing: Morning and early afternoon dosing optimal; avoid late evening.

Peptide Interactions

How to Reconstitute

Important: Always use bacteriostatic water (BAC). Sterile technique is essential.

1

Supplied as tablets, capsules, or powder

2

Use precision scale for powder

3

Sublingual enhances absorption

4

Can take with or without food

5

Pair with choline source

Dosing Calculator

Calculate your injection volume with visual dosing guide

FINAL CONCENTRATION
2.50mg/mL
Each milliliter contains 2.50 mg of peptide
VISUAL REFERENCE (RESEARCH USE ONLY)

To obtain 250 mcg from this solution:

Draw 0.10 mL=10 units

(1 mL = 100 units on any insulin syringe)

0102030405060708090100
00.10.20.30.40.50.60.70.80.91.0
0.10 mL
10 units

Draw to this mark for 250 mcg

This calculator is for research purposes only. Always verify calculations and consult protocols.

Quality Indicators

White crystalline powder

White to off-white without discoloration.

Third-party testing

COA showing ≥98% purity with HPLC.

Discoloration or clumping

May indicate degradation.

What to Expect

  • Days 1-3: Subtle cognitive clarity
  • Week 1: Noticeable memory recall improvement
  • Week 2-3: Enhanced learning capacity
  • Week 4-6: Peak cognitive benefits

Side Effects & Safety

Side Effects

  • Headache if not using choline
  • Avoid evening dosing - may affect sleep
  • Start with 10mg to assess response
  • Not recommended during pregnancy

When to Stop

  • Persistent headaches
  • Irritability
  • Sleep disturbance
  • After 8 weeks (cycle off)

References

2 Studies

Neuroprotection in Alzheimer's Model (2015)

Cellular | Human neurons | Reduced tau phosphorylation

Attenuated apoptosis and tau hyperphosphorylation in amyloid-beta toxicity.

Human Cognitive Trial (2008)

Human | 53 patients | 56 days | MMSE improved 26→29

Universal improvement with 1.8x fewer side effects vs piracetam.

Quick Start Guide

Typical Dose
10-20mg
How Often
1-3x daily, morning/afternoon
Where to Inject
Oral or sublingual
Timing
Morning preferred, pair with choline
Effects Timeline
Onset 20-60 min, peak 2 hours, duration 3-5 hours
Storage
Room temp, protect from moisture
Cycle Length
4-8 weeks
Break Between
2-4 weeks between cycles

Research Disclaimer

Omberacetam (Noopept) is sold for laboratory research purposes only and is not intended for human or animal consumption. The information provided on this page is compiled from published research, veterinary studies, and anecdotal reports for educational purposes. This content does not constitute medical advice, diagnosis, or treatment recommendations. Any research involving Omberacetam (Noopept) must comply with all applicable local, state, and federal regulations. BioInfinity Lab makes no claims regarding the safety or efficacy of Omberacetam (Noopept) for any purpose. Consult qualified professionals for any research applications.