For research and educational purposes only. Not intended for human consumption.
NAD+
Extensively Studied- •Sirtuin pathway activation research
- •DNA repair enhancement mechanisms
- •Anti-aging cellular rejuvenation data
Essential Cellular Coenzyme | Anti-Aging Therapy
Overview
What is NAD+?
Nicotinamide Adenine Dinucleotide (NAD+) is a vital coenzyme found in every cell that plays a crucial role in energy production, DNA repair, and cellular metabolism. As NAD+ levels naturally decline with age, supplementation can support cellular health, boost energy, enhance cognitive function, and promote longevity.
Key Benefits
Highest bioavailability (100%), rapid cellular uptake, immediate energy enhancement, bypasses digestive limitations.
Mechanism of Action
Direct delivery to bloodstream ensures maximum cellular availability for energy production, DNA repair, and sirtuin activation.
Molecular Information
Pharmacokinetics
Research Indications
Cellular Energy Production
Restores mitochondrial function and ATP synthesis capacity.
Metabolic Optimization
Enhances glucose and fat metabolism efficiency.
Exercise Performance
Improves oxygen utilization and endurance capacity.
Research Protocols
Disclaimer: NAD+ therapy should be administered under medical supervision, especially IV infusions. Start with lower doses to assess tolerance.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| General Wellness & Energy | 100-250mg | 1-2x weekly | IV or IM |
| Anti-Aging Protocol | 250-500mg | 2-3x weekly | IV infusion |
| Cognitive Enhancement | 500-1000mg | 1-2x weekly | IV infusion |
| Athletic Performance | 250-500mg | 2x weekly | IM injection |
| Recovery & Repair | 500-1000mg | 3x weekly | IV infusion |
| Maintenance Therapy | 100-250mg | 1x weekly | SubQ or IM |
Timing: Morning administration aligns with natural circadian rhythms and provides sustained energy throughout the day.
Peptide Interactions
How to Reconstitute
Important: Always use bacteriostatic water (BAC). Sterile technique is essential.
Clean work surface and wash hands thoroughly
Wipe tops of both vials with alcohol swabs
Draw appropriate amount of bacteriostatic water (typically 2-3ml for 500mg vial)
Inject water slowly into NAD+ vial, aiming at the glass wall
Gently swirl (do not shake) until completely dissolved
Draw prescribed dose using fresh needle
Inject at chosen site (IM: deltoid, glute, or thigh; SubQ: abdomen or thigh)
Store remaining solution refrigerated
Dosing Calculator
Calculate your injection volume with visual dosing guide
To obtain 250 mcg from this solution:
Draw 0.10 mL=10 units
(1 mL = 100 units on any insulin syringe)
Draw to this mark for 250 mcg
This calculator is for research purposes only. Always verify calculations and consult protocols.
Quality Indicators
Clear, colorless solution
NAD+ solution should be transparent without particles.
Proper refrigeration
Stored consistently at 2-8°C for potency.
Sterile technique
Use proper sterile injection procedures.
Reconstitution timing
Use within 28 days of mixing with bacteriostatic water.
Cloudy or discolored solution
May indicate contamination or degradation.
Room temperature storage
Heat degrades NAD+ rapidly.
What to Expect
- •Week 1-2: Initial energy improvements and mental clarity
- •Week 3-4: Enhanced physical performance and recovery
- •Week 5-8: Sustained energy levels and improved sleep quality
- •Week 9-12: Optimized metabolic function and cognitive benefits
Side Effects & Safety
Side Effects
- •Start with lower doses to assess tolerance
- •IV administration requires medical supervision
- •Monitor for injection site reactions
- •Avoid alcohol consumption during treatment
- •Maintain consistent dosing schedule for best results
When to Stop
- •Severe injection site reactions
- •Signs of allergic reaction
- •Persistent discomfort
- •As directed by healthcare provider
References
3 StudiesIntranasal NAD+ for TBI (2012)
Rats | 20 mg/kg intranasal | Post-TBI treatment | Hippocampal neuroprotection
Demonstrated that intranasal NAD+ delivery protected hippocampal neurons following traumatic brain injury.
Nicotinamide Riboside Safety Study (2019)
Human | 100-1000mg oral daily | 8 weeks | Well-tolerated, increased NAD+
Randomized clinical trial demonstrating long-term NR administration is safe and effectively elevates NAD+ metabolites.
Age-Associated NAD+ Decline (2012)
Human tissue analysis | Multiple organs | 10-50% decline with age
Foundational study showing NAD+ decreases in skin, brain, heart, and liver by 10-50% during adult aging.
Quick Start Guide
Research Disclaimer
NAD+ is sold for laboratory research purposes only and is not intended for human or animal consumption. The information provided on this page is compiled from published research, veterinary studies, and anecdotal reports for educational purposes. This content does not constitute medical advice, diagnosis, or treatment recommendations. Any research involving NAD+ must comply with all applicable local, state, and federal regulations. BioInfinity Lab makes no claims regarding the safety or efficacy of NAD+ for any purpose. Consult qualified professionals for any research applications.