For research and educational purposes only. Not intended for human consumption.
HCG
Extensively Studied- •FDA-approved fertility treatments
- •TRT testicular preservation protocols
- •LH receptor binding mechanism detailed
Human Chorionic Gonadotropin | LH Receptor Agonist
Overview
What is HCG?
Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone naturally produced by the placenta during pregnancy. It binds to and activates LH receptors, making it valuable for treating hypogonadism, infertility, and cryptorchidism. In TRT protocols, HCG maintains testicular function and preserves fertility. Banned by WADA
Key Benefits
Maintains testicular function during TRT, preserves fertility, prevents testicular atrophy, stimulates endogenous testosterone, induces ovulation in women.
Mechanism of Action
HCG binds to LH receptors on Leydig cells, stimulating testosterone biosynthesis. In women, it triggers final oocyte maturation. Half-life is 24-36 hours.
Molecular Information
Pharmacokinetics
Research Indications
Cryptorchidism
FDA-approved for prepubertal cryptorchidism. ~25% success rate.
Hypogonadotropic Hypogonadism
FDA-approved for secondary hypogonadism.
Ovulation Induction
FDA-approved trigger for final follicular maturation.
Research Protocols
Disclaimer: HCG is FDA-approved for specific indications. Discuss off-label use with your physician.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| TRT Adjunct (Low) | 250-500 IU | Every other day | SubQ or IM |
| TRT Adjunct (Standard) | 500-1000 IU | Twice weekly | SubQ or IM |
| HCG Monotherapy | 1500-2000 IU | 2-3 times weekly | IM |
Timing: Administer 2-3 times weekly, evenly spaced.
Peptide Interactions
How to Reconstitute
Important: Always use bacteriostatic water (BAC). Sterile technique is essential.
Clean stoppers with alcohol
Draw diluent (1-2 mL)
Inject slowly into HCG vial
Gently swirl
Store refrigerated 2-8°C, use within 30-60 days
Dosing Calculator
Calculate your injection volume with visual dosing guide
To obtain 250 mcg from this solution:
Draw 0.10 mL=10 units
(1 mL = 100 units on any insulin syringe)
Draw to this mark for 250 mcg
This calculator is for research purposes only. Always verify calculations and consult protocols.
Quality Indicators
White lyophilized powder
White to off-white powder in sealed vial.
Clear reconstituted solution
Completely clear after reconstitution.
Cloudy or discolored
Any turbidity indicates degradation.
What to Expect
- •Day 1-3: No immediate effects
- •Week 1-2: Testosterone increase on labs
- •Week 2-4: Testicular fullness noticeable
- •Month 2-3: Sperm count improvements
Side Effects & Safety
Side Effects
- •May cause gynecomastia due to increased estrogen
- •Headaches, mood swings
- •Risk of OHSS in women
- •Contraindicated in hormone-sensitive cancers
When to Stop
- •Signs of gynecomastia
- •Severe mood changes
- •Signs of blood clots
- •Any cancer diagnosis
References
1 StudiesSpermatogenesis Induction (2018)
Review | Hypogonadotropic hypogonadism | 70-90% success
Combined HCG/FSH therapy induces spermatogenesis.
View StudyQuick Start Guide
Research Disclaimer
HCG is sold for laboratory research purposes only and is not intended for human or animal consumption. The information provided on this page is compiled from published research, veterinary studies, and anecdotal reports for educational purposes. This content does not constitute medical advice, diagnosis, or treatment recommendations. Any research involving HCG must comply with all applicable local, state, and federal regulations. BioInfinity Lab makes no claims regarding the safety or efficacy of HCG for any purpose. Consult qualified professionals for any research applications.