Tissue Repair

BPC-157 is a synthetic 15-amino-acid peptide originally derived from a larger gastric protective protein fraction identified in stomach mucosa. It has attracted sustained scientific interest because it appears to interact with multiple biological pathways involved in tissue integrity, vascular signaling, and stress responses in preclinical research models.

GHK-Cu is a naturally occurring copper-binding tripeptide that promotes wound healing through keratinocyte migration, increased VEGF/bFGF expression, decorin and collagen production, elastin and glycosaminoglycan synthesis, while remodeling tissue via MMP-2/MMP-9 activation and TIMP-1/TIMP-2 modulation to organize collagen and elastin fibers.

TB-500 is a synthetic 7-amino-acid fragment (Ac-LKKTETQ) from thymosin beta-4's actin-binding site that promotes tissue repair through G-actin sequestration, ROCK1 downregulation, cell migration, progenitor cell mobilization, angiogenesis, and anti-inflammatory effects. Phase 2 human trials show 61% improvement in wound reepithelialization by day 7.

Ara 290 is an erythropoietin-derived peptide that activates tissue-protective pathways without stimulating red blood cells. FDA Orphan Drug status with Phase 2 trial success.

Thymosin Beta-4 is a naturally occurring 43-amino acid peptide that plays crucial roles in tissue repair, wound healing, and cellular regeneration. It promotes angiogenesis and reduces inflammation.

The Wolverine Stack combines BPC-157 and TB-500 for synergistic tissue repair. A 2021 clinical study showed 87.5% of patients experienced knee pain relief with this combination.

Cartalax is a synthetic tripeptide bioregulator that supports cartilage, connective tissue, and cellular regeneration through modulation of proliferation markers and apoptosis pathways.

The Glow Protocol is a multi-peptide skin rejuvenation complex featuring BPC-157, TB-500, and GHK-Cu for comprehensive anti-aging and tissue repair.

KLOW is a four-peptide regenerative blend (GHK-Cu + TB-500 + BPC-157 + KPV) building on the GLOW protocol with enhanced anti-inflammatory effects from KPV.