Experimental

FOXO4-DRI is a D-retro-inverso peptide that selectively induces apoptosis in senescent cells by disrupting FOXO4-p53 nuclear complexes, causing p53 nuclear exclusion, mitochondrial translocation, BAX activation, cytochrome C release, and caspase-3/7-mediated intrinsic apoptosis while sparing healthy cells.

Dihexa is a synthetic oligopeptide derived from angiotensin IV that acts as an HGF mimetic, binding hepatocyte growth factor with high affinity and enhancing c-Met receptor signaling to promote synaptogenesis 7-fold greater than BDNF, neurogenesis, and memory restoration in preclinical Alzheimer's models.

Melanotan I is a synthetic α-MSH analog that selectively targets MC1 receptors to stimulate melanin production. FDA-approved implant (SCENESSE®) exists for erythropoietic protoporphyria.

Adipotide is a chimeric peptide that targets and destroys blood vessels feeding white adipose tissue, causing rapid fat loss through apoptosis of fat cells. Highly experimental with significant side effects.

PEG-MGF is a pegylated form of the IGF-1 splice variant MGF that activates muscle satellite cells for repair and regeneration with extended half-life.

SLU-PP-332 is a synthetic 'exercise mimetic' that activates metabolic pathways engaged during physical exercise, showing 12% weight loss and 70% endurance increase in animal studies. NOT FOR HUMAN USE.