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Buy TB-500 (Thymosin Beta-4 Fragment) in the USA

TB-500 is the synthetic fragment of native Thymosin Beta-4 that researchers cite most often in regenerative-biology studies. BioInfinity Lab supplies ≥99% HPLC-verified TB-500 same-day from New York with a third-party Certificate of Analysis on every batch.

≥99% HPLC + MS puritySame-day NY shippingThird-party COA (Janoshik Analytical)

Available sizes — TB-500

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Why source TB-500 from BioInfinity Lab

TB-500 is a particularly sensitive peptide to source — synthesis of the 7-amino-acid fragment corresponding to residues 17–23 of Thymosin Beta-4 requires careful purification because related-sequence impurities can co-elute on lower-resolution analytical methods. BioInfinity Lab partners with Janoshik Analytical to validate every lot with HPLC + mass spectrometry, confirming both purity and the correct molecular mass. The COA is publicly referenced on this product page.

TB-500 in published research

Peer-reviewed publications describe TB-500 in models of cardiac protection, fibrosis modulation, and actin sequestration. The 2007 review in Expert Opinion on Biological Therapy provides a useful introduction to the multi-functional research peptide; the 2012 Annals NYAS paper covers cardiac-protection research literature in detail. See the PubMed citations on our /product/tb-500 page for primary sources.

Vial sizes and common research combinations

Our 5 mg vial is suitable for short research protocols; 10 mg supports extended studies. Researchers commonly investigate TB-500 alongside BPC-157 — a combination available pre-blended in our /product/bpc-157-tb-500 vial for protocol convenience.

Reconstitution and storage

Reconstitute lyophilized TB-500 with bacteriostatic water at 1–5 mg/mL per your laboratory's SOP. Lyophilized vials store at −20 °C; reconstituted solution at 2–8 °C, typically used within 30 days.

Same-day USA shipping

TB-500 orders placed before 2 PM ET ship the same day from our NY facility, with free shipping on orders over $200.

Research FAQ — TB-500

Frequently asked questions about this compound for laboratory researchers.

What is TB-500 and how is it studied?+
TB-500 is a synthetic fragment corresponding to amino acids 17–23 of the native protein Thymosin Beta-4. Published research investigates its role in actin sequestration, angiogenesis modulation, and migration of progenitor cells in tissue-injury models.
What concentrations are used in TB-500 research?+
Rodent and large-animal research papers cite a wide range, often 1–10 mg/kg administered intraperitoneally or subcutaneously. Researchers should follow their IRB protocol and the dosing reported in the cited literature.
How is TB-500 different from full-length Thymosin Beta-4?+
TB-500 represents an active fragment of the full 43-amino-acid Thymosin Beta-4 protein. Research suggests the fragment retains the actin-binding region thought to mediate several of TB-4's reported effects.
How should TB-500 be reconstituted and stored?+
Lyophilized TB-500 is typically reconstituted with bacteriostatic water at 1–5 mg/mL and stored at 2–8 °C after reconstitution. Lyophilized vials store at −20 °C. Refer to your laboratory's SOP and product COA.

Published research references

Peer-reviewed literature relevant to TB-500 research. Linked PubMed IDs open the original source.

  1. [1]Thymosin beta 4 and cardiac protection: implication in inflammation and fibrosis — Ann N Y Acad Sci (2012) · PMID 22737108
  2. [2]Thymosin beta-4: a multi-functional regenerative peptide — Expert Opin Biol Ther (2007) · PMID 17192546
  3. [3]Thymosin beta-4 and the anti-fibrotic effects on the heart — Ann N Y Acad Sci (2010) · PMID 21564349
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Reviewed by the BioInfinity Research Team
Content reviewed by our research and quality team — biochemistry-degreed reviewers working alongside our analytical lab partner (Janoshik Analytical). Every product page is cross-checked against the cited peer-reviewed literature and the current batch's third-party COA.
For laboratory research use only. Not for human or veterinary use. Content is informational and does not constitute medical advice.

Verified reviews — TB-500

1 verified buyer

5.0 / 5
thesaintnoahVerified buyer
Jun 8, 2026
Exceptional fast shipping and Customer Service

Amazing product, BioInfinity is the only place i am going to use in the future, thanks for the amazing customer service you are providing!

Reviews are submitted by verified buyers via per-order tokenized links. Reviews are evaluated for product-focused content; any review containing therapeutic claims (cured, treats, healed, etc.) may be edited or hidden to maintain compliance with FDA and platform guidelines.

Order TB-500 from BioInfinity Lab

Same-day shipping from New York, ≥99% HPLC-verified purity, and a third-party COA on every lot.

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For laboratory research use only. Not for human or veterinary use.