Buy IGF-1 LR3 in the USA

Native IGF-1 has a relatively short plasma half-life in research models because it binds tightly to IGF-binding proteins (IGFBPs) that clear it from circulation. IGF-1 LR3 carries two modifications — a substituted arginine at position 3 and a 13-amino-acid N-terminal extension — that together reduce IGFBP binding and extend the reported plasma half-life dramatically.

Published research literature describes IGF-1 LR3 with a plasma half-life cited around 20–30 hours in research models, compared to roughly 12–15 minutes for native IGF-1. This pharmacokinetic difference is the primary reason research protocols cite IGF-1 LR3 rather than native IGF-1 when investigating sustained IGF-receptor activation.

IGF-1 LR3 research literature spans cell-culture studies (where the compound is widely used as a stable IGF-receptor agonist) and animal-model research investigating growth-factor signaling pathways. Researchers should reference compound-specific methodology in cited publications and follow IRB-approved protocols.

BioInfinity Lab supplies lyophilized IGF-1 LR3 in 1 mg and 2 mg research vials. Lyophilized at −20 °C protected from light; reconstituted with bacteriostatic water at 2–8 °C and typically used within 30 days. Some research protocols cite reconstitution with mild acetic acid solution per compound-specific stability data — consult the COA and your laboratory's SOP.

IGF-1 LR3 orders placed before 2 PM ET ship same-day from our New York facility, Monday through Friday. Every lot includes a Janoshik Analytical HPLC + MS Certificate of Analysis. Free shipping over $200.